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Changes in laryngopharyngeal reflux immediately following uvulopalatopharyngoplasty to own obstructive sleep apnea: An observational research

Changes in laryngopharyngeal reflux immediately following uvulopalatopharyngoplasty to own obstructive sleep apnea: An observational research

Shisheng Li, Company out-of Otolaryngology Head and you will Shoulder Procedures, The next Xiangya Medical, Central Southern College or university, Changsha, Hunan 410000, China.

Shisheng Li, Agencies off Otolaryngology Head and you can Shoulder Businesses, The second Xiangya Medical, Main Southern area College, Changsha, Hunan 410000, China.


To imagine laryngopharyngeal reflux (LPR) change immediately following uvulopalatopharyngoplasty (UPPP) getting obstructive sleep apnea (OSA) using the reflux danger signal list (RSI) and you will reflux interested in get (RFS) questionnaires.


A total of 91 participants was basically employed and you can divided into three groups: handle (letter = 27), OSA lighter so you’re able to reasonable (letter = 29), and you will OSA major (letter = 35) teams predicated on polysomnography. All of the participants completed brand new preoperative RSI, and underwent blinded assessment on the videolaryngoscopy making use of the RFS questionnaire. Thirty-five OSA customers just who undergone UPPP surgery finished postoperative polysomnography and you may forms again after a 6-few days pursue-right up.


The RSI score and RFS were higher in patients with OSA than in those without OSA. Patients with severe OSA also had a higher RSI score and RFS than those with mild to moderate OSA. Apnea and hypopnea index degree and percentage of recording time for <90% oxygen saturation showed positive correlation with LPR symptoms. But the lowest blood oxygen saturation during the recording time was negatively correlated with LPR symptoms. The mean RSI score and RFS before UPPP surgery were ± 4.85 and ± 4.80, after surgery decreasing to 9.53 ± 4.16 and 8.65 ± 4.87, respectively (P <.05). In 25 patients where surgery was successful, RSI scores, RFSs and individual RSI variables decreased after surgery.


LPR attacks all are among OSA customers, together with coexistence regarding OSA and you may LPR cannot be ignored. Successful UPPP procedures potentially decreases LPR symptoms and you will improves laryngoscopic cues because of the relieving bed breathing problems.

step one Inclusion

Obstructive anti snoring (OSA) is actually an ever-increasing fitness concern. Whenever 2%–4% out of middle-aged someone have OSA. step 1 OSA are characterized by repetitive failure and you can reopening of top airway during sleep ultimately causing periodic hypoxia and you will bed fragmentation. 2 Periodic hypoxia are an ailment when apnea/hypopnea occurs, and you can outdoors have for the bloodstream was less. Intermittent hypoxia results in general pain and you may oxidative fret and you may mation. step 3 To relieve which episodes, continued positive airway stress (CPAP) otherwise operations are all treatments placed on OSA.

CPAP decreases reflux situations and you may advances scientific signs and symptoms of gastroesophageal reflux condition (GERD) and you will laryngopharyngeal reflux (LPR) in the patients which have OSA, instance acid reflux issues. 4-6 Given that a great and you can noninvasive treatment for OSA, CPAP retains a certain self-confident tension about upper airway in order to improve higher airway failure. Research has shown you to definitely CPAP minimizes each other GERD and LPR attacks because of the broadening esophageal inner tension, cuatro, eight and reflex contraction of straight down esophageal anal sphincter (LES), 8 limiting reflux cycle and you may reducing esophageal acidification. OSA and you will LPR are a couple of conditions that produce persistent top airway pain. In OSA clients, coexistence with LPR is really frequent, becoming found in 20%–67% regarding customers. 9, 10 While the relationship ranging from OSA and you may LPR has been has just investigated, it however stays controversial. Although some research has showed you to definitely CPAP therapy somewhat enhances reflux periods inside OSA clients, 11 simply pair has actually examined the result of surgery treatment getting OSA on the reflux problem https://hookupranking.com/lesbian-hookup/.

Uvulopalatopharyngoplasty (UPPP) are a commonly recognized procedures getting OSA twelve and you can very first suggested of the Fujita et al. thirteen It has been recently improved fourteen toward goal of decreasing the oropharyngeal congestion by removing redundant mucosal folds, hypertrophic tonsils, and you can a very thickened and you can elongated silky palate. fifteen UPPP can get alleviate the severity out-of OSA for the customers whoever obstruction website are at this new palatopharyngeal peak.

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